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On of 1st draft from the manuscript. C.-L.C. contributed
On of 1st draft from the manuscript. C.-L.C. contributed to verification of information. G.H.-Y.L., S.K.-K.L., I.C.-K.W., J.K.-P.C. and C.-L.C. contributed to the interpretation of final results and writing of the manuscript. All authors have read and agreed to the published version on the manuscript. Funding: This research received no external funding. Institutional Overview Board Statement: All of the GWAS/GWAS meta-analysis from which the summary statistics had been extracted from had obtained ethics approval in the respective institutional overview board. Informed Consent Statement: Each of the GWAS/GWAS meta-analysis from which the summary statistics were extracted from had obtained informed consent from the study participants. Information Availability Statement: Summary statistics of genetic instruments might be obtained in the web sites listed on the referenced GWAS or GWAS meta-analysis. Acknowledgments: We express our gratitude to all study participants with the respective GWAS/GWAS meta-analysis from which the summary statistics of this study have been obtained from. Conflicts of Interest: We declare no possible conflict of interest.
Journal ofClinical MedicineArticleRobotic vs. Transsternal Thymectomy: A Single Center Expertise more than 10 YearsLuis Filipe Carbazeran Phosphodiesterase (PDE) azenha 1, , Robin Deckarm 1, , Fabrizio Minervini two , Patrick Dorn 1 , Jon Lutz 1 and Gregor Jan Kocher 1, Division of Common Thoracic Surgery, Bern University Hospital, University of Bern, 3010 Bern, Switzerland; [email protected] (L.F.A.); [email protected] (R.D.); [email protected] (P.D.); [email protected] (J.L.) Department of Thoracic Surgery, Cantonal Hospital Lucerne, 6000 Lucerne, Switzerland; [email protected] Correspondence: [email protected]; Tel.: +41-31-632-37-45 The authors contributed equally to this manuscript.Citation: Azenha, L.F.; Deckarm, R.; Minervini, F.; Dorn, P.; Lutz, J.; Kocher, G.J. Robotic vs. Transsternal Thymectomy: A Single Center Encounter over 10 Years. J. Clin. Med. 2021, 10, 4991. https://doi.org/ 10.3390/jcm10214991 Academic Editors: Monica Casiraghi and Luca Bertolaccini Received: 27 September 2021 Accepted: 25 October 2021 Published: 27 OctoberAbstract: Introduction: Thymomas would be the most typical tumors from the mediastinum. Traditionally, thymectomies have been performed by means of a transsternal (TS) approach. Using the development of robot-assisted thoracic surgery (RATS), a promising, minimally invasive, option surgical method for performing a BPAM344 Purity thymectomy has been created. Inside the present paper, the oncological and surgical outcomes from the TS vs. RATS thymectomies are discussed. Approaches: For the RATS thymectomy, two 8 mm working ports and a single 12 mm camera port have been employed. Within the transsternal approach, we performed a median sternotomy and resected the thymic tissue completely, in some circumstances en bloc with aspect of the lung and/or, far more frequently, a partial pericardiectomy with consequent reconstruction employing a bovine pericardial patch. The decisions for making use of the TS vs. RATS approaches had been primarily according to the suspected tumor invasion on the surrounding structures around the preoperative CT scan and tumor size. Benefits: Amongst January 2010 and November 2020, 149 sufferers have been submitted for an anterior mediastinal tumor resection at our institution. A total of 104 sufferers met the inclusion criteria. One procedure was performed via a hemi-clamshell incision. A total of 81 (78 ) sufferers underwent RATS procedures, and 22 (21.1 ) sufferers were treat.

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