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Olyethylene glycol unit with high molecular the elongation tensile strength with a rise in the crosslinking density and increased the elongation at break by introducing a polyethylene glycol unit with high molecularFigure 8. UV is spectra of HPC-based hydrogels obtained in the following concentration and dose. Figure eight. UV is spectra of HPC-based hydrogels obtained in the following concentration and dose. HPC/23G (20/0.2 wt. , 30 kGy) and hydrogels obtained in the following concentration and dose. Figure eight. UV is spectra kGy) and HPC/23G/HEMA (20/0.2/2 wt. , 50 kGy). HPC/23G (20/0.2 wt. , 30of HPC-basedHPC/23G/HEMA (20/0.2/2 wt. , 50 kGy). HPC/23G (20/0.2 wt. , 30 kGy) and HPC/23G/HEMA (20/0.2/2 wt. , 50 kGy).Appl. Sci. 2021, 11, x FOR PEER Review Appl. Sci. 2021, 11, x FOR PEER Review Appl. Sci. 2021, 11,9 of 11 9 of of 11 9mobility among the HPC composed of a rigid Heptelidic acid Caspase glucose ring. The introduction of poly mobility amongst the HPC composedglycolrigid with higher molecular break by the network polyethylene of a unit glucose ring. The introduction of poly (HEMA) inintroducing apolymer elevated the mobility of your networkmobility between the polymer, resulting (HEMA) within the network polymer enhanced theintroductionthe poly (HEMA) in the network mobility of of network polymer, resulting inHPC composed of in rigid glucose ring. The from the hydrogels. The tensile strength from the a additional increase a the elongation at break inpolymer increasedin the elongation at break with the hydrogels. The tensile strength with the a further improve the mobility on the network polymer, HEMA-based contact lens supplies is reported to be in theresulting 0.1.six MPa raise in selection of within a further [30]. The HEMA-based contact lens supplies is reportedtensile strength of of 0.1.6 MPa [30]. The to become in the range the HEMA-based make contact with the elongation at break in the hydrogels. The hydrogel are inside the array of those of mechanical properties in the HPC/23G/HEMA mechanical properties in the HPC/23G/HEMA hydrogel are inside the range of properties lens components is reported to become within the the HPC/23G/HEMA hydrogel might be those of HEMA-based make contact with lens components, sorange of 0.1.six MPa [30]. The mechanicalused as a HEMA-based get in touch with lens materials, so the HPC/23G/HEMAthose of HEMA-based contact of the HPC/23G/HEMA hydrogel are within the array of hydrogel could be utilized as a make contact with lens material. contact lens material. HPC/23G/HEMA hydrogel could be employed as a contact lens material. lens materials, so the0.24 0.24 0.2 0.two 0.16 0.16 0.12 0.12 0.08 0.08 0.04 0.04 0Stress (MPa) Stress (MPa)HPC HPC HPC/23G HPC/23G HPC/23G/HEMA HPC/23G/HEMA0204060 80 one hundred 120 140 60 80 one hundred 120 140 Strain Strain Figure 9. 9. Tension train curves of HPC-basedhydrogels. The HPC-based hydrogels were prepared at Figure Tension train curves of HPC-based hydrogels. The HPC-based hydrogels were prepared Figure 9. Calyculin A Biological Activity Anxiety train curves and dose: HPC/23G/HEMA = 20/0/0 wt. , hydrogels were wt. , 30 HPC-based 50 at the following concentration of HPC-based hydrogels. The = 20/0/0 wt. , kGy; 20/0.2/0prepared the following concentration 50 kGy; 20/0.2/0 wt. , at the20/0.2/2 wt. , 50 kGy. and dose: HPC/23G/HEMA = 20/0/0 wt. , 50 kGy; 20/0.2/0 wt. , 30 following concentration and dose: HPC/23G/HEMA kGy;kGy; 20/0.2/2 wt. , 50 kGy. 30 20/0.2/2 wt. , 50 kGy. kGy;Elongation at break Elongation at break 150 150 120 120 90 90 60 60 30 30 0 0 0.0 0.HPC/23G/HEMA HPC/23G/HEMA 20/0/0 20/0/0 20/0.2/0 20/0.2/0 20.

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